Fri Sep 19 2025

29 articles - From Friday Sep 12 2025 to Friday Sep 19 2025

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Guidelines

Guidelines and related publications, position statements, white papers, technical reviews, consensus statements, etc…


Meta-analysis

meta-analyses and systematic reviews

Am J Clin Nutr

Effects of carbohydrate-restricted diets and macronutrient replacements on cardiovascular health and body composition in adults: A meta-analysis of randomized trials.

CRDs improved cardiovascular health and body composition, especially in diets with combined macronutrient replacement. Potential adverse effects, including LDL elevation and lean mass loss, warrant clinical monitoring. Registration number For body composition PROSPERO CRD420251043066 ( for cardiovascular health CRD420251011748 (

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Original articles

RCT, clinical trials, retrospective studies, etc…

Am J Clin Nutr

Associations of body mass index, waist circumference, and weight-adjusted waist index with body composition and biomarkers: A multinational pooled analysis.

Our data suggest that WWI is associated with unhealthy body composition (high fat, low fat-free mass) in populations of diverse age, sex, and race/ethnicities and may serve as an alternative index to BMI and WC.

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Can correction of low vitamin D status in infancy program for a leaner body composition?: a post-trial follow-up study of whole body lean mass in early childhood.

The greater whole body lean mass observed in infants in our published trial of 1000 IU/d of vitamin D supplementation compared to 400 IU/d was maintained post-trial at 24 months in accordance with greater length. Confirmation of these observations, and whether these extend into later childhood, requires new trials.

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Impact of sustainable diets on micronutrient intakes and status: outcomes of the MyPlanetDiet randomized controlled trial.

A diet based on sustainable dietary principles lowered dietary GHGE and several MNs, despite provision of daily servings of dairy, three weekly servings of animal protein and two servings of fish. These findings show that MNs should be considered in developing environmentally protective diets. Clinical trial registry (NCT05253547).

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Interaction between dietary cholesterol intake and genetic variants for cholesterol absorption in relation to coronary artery disease mortality: a prospective analysis in the Singapore Chinese Health Study.

DC intake was more strongly associated with CAD mortality in Singapore Chinese with greater genetic susceptibility to cholesterol absorption.

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Magnesium Treatment Increases Gut Microbiome Synthesizing Vitamin D and Inhibiting Colorectal Cancer: Results from a Double-Blind Precision-based Randomized Placebo-Controlled Trial.

In individuals with adequate TRPM7 function, Mg supplementation increases abundance of C. maltaromaticum and F. prausnitzii. Clinical trial registry This trial was registered on ClinicalTrials.gov as NCT04229992 ( The parent study is registered as NCT03265483, and another relevant study is registered as NCT01105169.

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The effect of Milk Fat Globule Membrane phospholipid supplementation on cognitive function in older adults with subjective memory complaints-a randomized, double blind, placebo-controlled trial.

While no significant effects were evident for cognition function, subjective alertness during cognitive testing was improved in the High-dose group. Reduced inflammation, cholesterol and LDL impacts for long-term cardiovascular health, linked with cognitive decline in ageing. MFGM supplementation positively impacted Active B12 (High and Low dose) and Homocysteine (High dose only), which have been associated with brain health. Longer study durations are needed to demonstrate cognitive benefits. Clinical trial registry number and website where it was obtained Australian New Zealand Clinical Trials Registry (ACTRN12620000270910);

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The effect of muscle quality index on the risk of adverse health outcomes: a prospective cohort study of 355,209 adults.

Our findings highlight the importance of enhancing muscle quality to prevent chronic diseases and unveil underlying mechanisms.

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Vitamin C Status across the Spectrum of Chronic Kidney Disease and Healthy Controls: a Cross-sectional Study.

VitC inadequacy and deficiency are common in CKD. Inadequate intake and removal by dialysis may contribute. In healthy individuals eGFR was inversely associated with plasma VitC. Our findings highlight the importance of monitoring VitC status in CKD, and represent a potential target for intervention. Future research could evaluate potential health effects of improving VitC status in CKD.

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Weight-adjusted-waist index, estimated glucose disposal rate, C-reactive protein, and mortality risks among individuals with type 2 diabetes: two prospective cohort studies in China and the UK.

High WWI levels were associated with increased risks of all-cause, cardiovascular, and non-cardiovascular mortality among individuals with T2D, and eGDR and CRP mediated their associations. Our study highlights the value of WWI in identifying high-risk individuals and the potential of monitoring and intervening in eGDR and CRP to prevent mortality in people with T2D.

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Liver Transpl

Evaluating the representativeness and validity of cosmos as a novel, large-scale, real-world data source for liver transplant research.

The associations of clinical factors with survival were similar across both groups. Cosmos database demonstrated acceptable generalizability to the general US LT recipient population, which may advance LT research through a better understanding about LT recipients' experiences and outcomes.

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Evaluation of low fibrinolytic activity by rotational thromboelastometry and outcomes in liver transplantation: A single centre prospective study.

LFA identified using ROTEM is a significant predictor of adverse outcomes, including splanchnic thrombosis and 28-day mortality, in LT patients. The real-time diagnostic capability of ROTEM offers critical prognostic insights and may guide therapeutic interventions to mitigate the thrombotic risk. These findings highlight the need for further multicenter studies to confirm the utility of ROTEM in LT and investigate the molecular mechanisms underlying LFA.

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Is there a place for deceased donor liver transplantation for colorectal metastases in the united states? Feasibility of a protocol utilizing machine perfusion.

These findings support the viability of DDLT for CRLM using advanced perfusion, contingent on strict protocol adherence. Center-specific waitlist dynamics must inform the choice between DDLT and living donor liver transplant(LDLT).

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Pancreas

Alternative Splicing of Secretin Receptor (SCTR) and its low Expression Drive the Occurrence of Pancreatic Ductal Adenocarcinoma.

This study provides novel insights into identifying potential therapeutic targets for pancreatic cancer, highlighting that SCTR may serve as a promising prognostic and diagnostic biomarker, with its low expression significantly associated with poor clinical outcomes in PDAC.

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Clinical Characteristics of Acute and Chronic Pancreatitis in Children and Impact of Obesity.

Obesity significantly impacted both length of hospital stay and AP severity in Asian children.

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Efficacy of Perfusion Computed Tomography in Early Prediction of Post-endoscopic Retrograde Cholangiopancreatography Pancreatitis.

Early perfusion CT findings after ERCP could predict PEP development in high-risk patients.

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Syndecan-1 is a Key Mediator of Entosis and Cellular Competition in Pancreatic Cancer.

These results suggest that SDC1-mediated entosis enhances tumor aggressiveness by contributing to cellular competition and heterogeneity. Our study sheds light on the critical role of SDC1 in promoting CIC formation and cancer progression, highlighting its potential as a therapeutic target to disrupt entotic mechanisms in PDAC.

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Pancreatology

Prediction model for mutation detection via circulating tumor DNA analysis in pancreatic cancer.

We developed and validated a predictive model for KRAS mutations. This model may be a useful clinical decision-making tool for liquid CGP in patients with PC.

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Reviews&Editorials

Plenty of the editorials are available as full text through the publisher website using the provided link

Am J Clin Nutr

Rising global burden of sugar-sweetened beverage consumption- Urgent need for action.

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Miscellaneous

misc publications eg case reports, tools of the trade, images of the month, etc…

Liver Transpl

Editorial: Porcine liver xenotransplantation-from bridge to allotransplant to clinical reality.

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From gut to graft: Can microbiota shape pediatric liver transplant outcomes?

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Reframing the narrative around non-utilization: Quality and geography in the era of machine perfusion.

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Robotic liver transplantation: Minimally invasive, maximally disruptive.

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Workload, compensation, and institutional support among U.S. transplant hepatologists: Results of a National Survey.

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Pancreas

Dana K. Andersen, MD Leader, Visionary, Colleague and Friend for the Pancreas Community.

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Letters&Replies

Letters to the editors and authors’ replies

Am J Clin Nutr

Calling Guidance Evidence-Based When It Is Not Is Against the Ethos of Science.

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Skeletal Muscle and Fat-Free Mass: Related but Distinct Concepts in Body Composition.

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We need to bridge nutritional and pharmacological research for long-term successful implementation of weight loss medication in practice.

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Pancreatology

Comment on "Concealed pancreatic cancer in acute pancreatitis: Early MRCP and EUS surveillance improves prognosis and identifies high-risk patients".

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